Artikkelen undersøker hvordan NIPT ble vedtatt implementert i det norske fosterdiagnostiske systemet gjennom en fagligpolitisk prosess mellom 2012 og 2017. Prosessen innebar at Nasjonalt kunnskapssenter for helsetjenesten, Helsedirektoratet, Bioteknologirådet og Helse- og Omsorgsdepartementet ga sine vurderinger av testen og sine råd omkring en eventuell innføring. Artikkelen viser at det i denne prosessen foregikk en forsiktig tilnærming eller sammensmelting mellom de tradisjonelt helt ulike måtene å forstå og å ramme inn fosterdiagnostikk på i Norge, dvs. i en ‘autonomi/ behandlingsramme’ og en (...) ‘sorteringsramme’. Artikkelen argumenterer videre for at denne tilnærmingen eller konvergensen var mulig fordi prosessen ble holdt innenfor de fagligpolitiske byråkratiene, og de ulike etatene var innstilt på å ‘samarbeide’ om å inkludere både kunnskap og verdier fra begge rammene i sine tilrådninger. Politikk for fosterdiagnostikk er imidlertid et svært politisk betent område i Norge, og denne konvergensen var et skjørt byggverk. Den sprakk da også opp i løpet av tre uker i mai 2020, da Fremskrittspartiet plutselig inngikk et ‘bioteknologiforlik’ med Arbeiderpartiet og SV etter at de hadde gått ut av Solbergregjeringen. Dermed endte spørsmålet om implementeringen av NIPT i Stortinget, hvor konvergensen i den fagpolitiske prosessen ble erstattet av de tradisjonelle frontene, og de gamle innrammingene igjen ble ‘satt i arbeid’. Artikkelen diskuterer avslutningsvis kort de bortimot uløselige dilemmaene disse innrammingene både representerer og produserer. Nøkkelord: NIPT, fosterdiagnostikk, humanmedisinsk bioteknologi, regulering English Title: Fetal diagnostics between medicine and ethics: Implementation of Prenatal Invasive Testing in a turbulent policy area: The article examines how the decision to implement Prenatal Invasive Testing in the Norwegian Fetal Diagnostic System was reached through a professional policy process between 2012 and 2017. The process involved the Norwegian Research Centre for Health Services, the Norwegian Directorate of Health, the Norwegian Biotechnology Advisory Board and the Ministry of Health and Care Services, which provided their individual assessments and advice regarding the potential implementation of the test. The article finds that a careful convergence took place between traditionally opposing ways to understand and frame fetal diagnostics in Norway – either as a ‘treatment frame’ or a ‘sorting frame’. The article further argues that this convergence was possible because the process was kept within these bureaucracies, and that the different agencies were willing to collaborate to include knowledge and values from both frames in their recommendations. However, policy for fetal diagnostics is a very turbulent political area in Norway, and this convergence was a fragile construction. During three weeks in May 2020, the convergence collapsed when the Norwegian Progress Party suddenly entered a “biotechnology settlement” with the Labour Party and the Socialist Left Party after exiting the conservative Government coalition. Hence, the question of implementing NIPT ended up in the Norwegian Parliament, where the convergence from the professional policy process was replaced by the traditional fronts, and the old framings were again set in motion. Lastly, the article briefly discusses the almost unsolvable dilemmas these framings both produce and represent. Keywords: NIPT, non-invasive prenatal testing, fetal diagnostics, medical biotechnology, regulation. (shrink)

Insulin‐dependent diabetes mellitus (IDDM) is an autoimmune disease whose etiology is complex. Both genetic susceptibility, which is polygenic, and environmental factors, including virus infections, appear to be involved in the development of IDDM. In this review, we have tried to balance the discussion of diabetes by examining both immunological and virological perspectives. Several mouse models, including viral and non‐viral models, have been used to study diabetes. For this review, we include lessons gleaned from the non‐obese diabetic (NOD) mouse and from (...) mouse models of coxsackievirus‐ and encephalomyocarditis‐virus‐induced diabetes. Finally, we present a multi‐stage model in which several viral infections, including the coxsackieviruses, are postulated to play a role in the autoimmune destruction of pancreatic beta cells. (shrink)

Recent developments in AI programming allow for new applications: individualized chatbots which mimic the speaking and writing behaviour of one specific living or dead person. ‘Deathbots’, chatbots of the dead, have already been implemented and are currently under development by the first start-up companies. Thus, it is an urgent issue to consider the ethical implications of deathbots. While previous ethical theories of deathbots have always been based on considerations of the dignity of the deceased, I propose to shift the focus (...) on the dignity and autonomy of the bereaved users of deathbots. Drawing on theories of internet-scaffolded affectivity and on theories of grief, I argue that deathbots may have a negative impact on the grief process of bereaved users and therefore have the potential to limit the emotional and psychological wellbeing of their users. Deathbot users are likely to become dependent on their bots which may make them susceptible to surreptitious advertising by deathbot providing companies and may limit their autonomy. At the same time, deathbots may prove to be helpful for people who suffer from prolonged, severe grief processes. I caution against the unrestricted usage of deathbots and suggest that they should be classified as medical devices. This classification would not the least mean that their non-harm, as well as their helpfulness for people suffering from prolonged grief needs to be proven and that their potential for autonomy infringements is reduced. (shrink)

Zsfassung in dt. und engl. Sprache. - Dt. Zsfassung u.d.T.: Fragen und Perspektiven des Transzendentalismus.

Epistemic exploitation occurs when privileged persons compel marginalized persons to educate them about the nature of their oppression. I argue that epistemic exploitation is marked by unrecognized, uncompensated, emotionally taxing, coerced epistemic labor. The coercive and exploitative aspects of the phenomenon are exemplified by the unpaid nature of the educational labor and its associated opportunity costs, the double bind that marginalized persons must navigate when faced with the demand to educate, and the need for additional labor created by the default (...) skepticism of the privileged. I explore the connections between epistemic exploitation and the two varieties of epistemic injustice that Fricker (2007) identifies, testimonial and hermeneutical injustice. I situate epistemic exploitation within Dotson’s (2012; 2014) framework of epistemic oppression, and I address the role that epistemic exploitation plays in maintaining active ignorance and upholding dominant epistemic frameworks. (shrink)

Individuals can do a broad variety of things with their words and enjoy different degrees of this capacity. What moderates this capacity? And in cases in which this capacity is unjustly disrupted, what is a good explanation for it? These are the questions I address here. I propose that speech capacity, understood as the capacity to do things with your words, is a structural property importantly dependent on individuals' position in a social structure. My account facilitates a non-individualistic explanation of (...) cases in which speech capacity is undermined due to speaker's perceived social identity, e.g. episodes of silencing. Instead of appealing to interlocutors' implicit bias against speaker's identity, a structural approach refers to the positions interlocutors occupy in the social structure and the discursive conventions operating upon those positions. I articulate my proposal drawing on the notion of affordances. Each position within a social structure is associated with its own range of speech affordances. Thus, speech capacity is a function of the probability distribution of speech affordances across positions in the structure. (shrink)

This article discusses the category of foreigner in the context of academia. In the first part I explore this category and its philosophical significance. A quick look at the literature reveals that this category needs more attention in analyses of dimensions of privilege and disadvantage. Foreignness has peculiarities that demarcate it from other categories of identity, and it intersects with them in complicated ways. Devoting more attention to it would enable addressing issues affecting foreigners in academia that go commonly unnoticed. (...) In the second part of the article I argue that current efforts to make academia a more inclusive environment should address the disadvantages that many foreign academics face. I focus on two senses of foreigner: working and living in a country that is not your country of origin, and being a nonnative speaker of the language in which you work. (shrink)

Książka zawiera wybrane teksty najważniejszych myślicieli zaliczanych do dwóch najbardziej znaczących kierunków neokantowskich, a mianowicie do szkoły badeńskiej i szkoły marburskiej. Szkoły te wyłoniły się w konsekwencji podziałów, jakie dokonywały się w ramach neokantyzmu, niezwykle złożonego kierunku filozoficznego drugiej połowy XIX wieku i początków wieku XX. Mówienie o neokantyzmie jest złożone, gdyż nie można podać ani daty jego powstania, ani też daty zakończenia, co przysparza wielu kłopotów z jego historycznym określeniem. Pomijając wszelkie trudności klasyfikacyjne, antologia ogranicza się do zaprezentowania poglądów (...) dwóch najważniejszych szkół. Poglądy szkoły badeńskiej ukazują teksty Wilhelma Windelbanda i Heinricha Rickerta, Emila Laska i Brunona Baucha. Natomiast poglądy szkoły marburskiej prezentują teksty Hermanna Cohena i Paula Natorpa oraz ich najwybitniejszych uczniów, tzn. Ernsta Cassirera i Nicolaia Hartmanna. Autorzy żywią przekonanie, że zamieszczone teksty są najbardziej reprezentatywne dla neokantyzmu prezentowanych szkół. (shrink)

The question whether ethical behavior is biologically determined may refer either to thecapacity for ethics (e.i., the proclivity to judge human actions as either right or wrong), or to the moralnorms accepted by human beings for guiding their actions. My theses are: (1) that the capacity for ethics is a necessary attribute of human nature; and (2) that moral norms are products of cultural evolution, not of biological evolution.Humans exhibits ethical behavior by nature because their biological makeup determines the presence (...) of the three necessary, and jointly sufficient, conditions for ethical behavior: (i) the ability to anticipate the consequences of one's own actions; (ii) the ability to make value judgements; and (iii) the ability to choose between alternative courses of action. Ethical behavior came about in evolution not because it is adaptive in itself, but as a necessary consequece of man's eminent intellectual abilities, which are an attribute directly promoted by natural selection. (shrink)

Structural gaslighting arises when conceptual work functions to obscure the non-accidental connections between structures of oppression and the patterns of harm they produce and license. This paper examines the role that structural gaslighting plays in white feminist methodology and epistemology using Fricker’s (2007) discussion of hermeneutical injustice as an illustration. Fricker’s work produces structural gaslighting through several methods: i) the outright denial of the role that structural oppression plays in producing interpretive harm, ii) the use of single-axis conceptual resources to (...) understand intersectional oppression, and iii) the failure to recognize the legacy of women of color’s epistemic resistance work surrounding the issue of sexual harassment in the workplace. I argue that Fricker’s whitewashed discussion of epistemic resistance to sexual harassment in the United States is a form of structural gaslighting that fails to treat women of color as knowers and exemplifies the strategic forgetting that is a central methodological tactic of white feminism. (shrink)

In her book Iris Murdoch, Gender and Philosophy, Sabina Lovibond argues that Iris Murdoch's philosophical and literary work is covertly dedicated to an ideology of female subordination. The most central and interesting aspect of her multifaceted argument concerns Murdoch's focus on the individual person's moral self-scrutiny and transformation of consciousness. Lovibond suggests that this focus is antithetical to the kind of communal and structural criticism of society that has been essential for the advance of feminism. She further reads Murdoch's dismissal (...) of “structuralism” as proof of Murdoch's alleged conservatism and neglect of feminist concerns. In this article I will argue that this line of argument—though not completely off-base concerning the awkwardness of Murdoch's relation to feminism— gives a misleading picture of Murdoch's philosophical and ideological position, and establishes a problematic antagonism between moral self-scrutiny and social criticism, which a closer look at Murdoch's work can help us overcome. (shrink)

Traditionally, empiricism has relied on the specialness of human observation, yet science is rife with sophisticated instrumentation and techniques. The present article advances a conception of empirical evidence applicable to actual scientific practice. I argue that this conception elucidates how the results of scientific research can be repurposed across diverse epistemic contexts: it helps to make sense of how evidence accumulates across theory change, how different evidence can be amalgamated and used jointly, and how the same evidence can be used (...) to constrain competing theories in the service of breaking local underdetermination. (shrink)

In this paper I discuss the viability of the claim that at least some forms of moral theory are harmful for sound moral thought and practice. This claim was put forward by e.g. Elisabeth Anscombe ( 1981 ( 1958 )) and by Annette Baier, Peter Winch, D.Z Phillips and Bernard Williams in the 1970’s–1980’s. To this day aspects of it have found resonance in both post-Wittgensteinian and virtue ethical quarters. The criticism has on one hand contributed to a substantial change (...) and broadening of the scope of analytic moral philosophy. On the other hand it is, at least in its most strongly anti-theoretical formulations, now broadly considered outdated and—to the extent that it is still defended—insensitive to the changes that have occurred within the field in the last 20–30 years. The task of this paper is to relocate the anti-theoretical critique into the field of analytic ethics today. (shrink)

In this note, my aim is to point out a phenomenon that has not received much attention; a phenomenon that, in my opinion, should not be overlooked in the professional practice of philosophy, especially within feminist efforts for social justice. I am referring to the way in which being a non-native speaker of English interacts with the practice of philosophy.1 There is evidence that non-native speakers are often perceived in prejudiced ways. Such prejudiced perception causes harm and, more importantly, constitutes (...) wrongdoing. As in other cases of prejudiced perception and biased behavior, it would be pretentious and misguided to expect philosophers and the philosophy profession to be free from this vice. There are good reasons to think that this prejudiced perception is bad not only for the persons who are perceived in such a way, but also for the profession, for it might make us miss important things that could improve philosophy in general. I claim we should be more sensitive to this phenomenon, both out of concern for justice, and for the sake of doing better philosophy. (shrink)

In this article, I argue that the main contribution of Hegel's philosophy of right to the contemporary political debate is that it opens a window on the idea that liberalism and individual freedom are incompatible. My main thesis is that the liberal conception of the State and law, structured from a nonrelational account of singularity, ends up denying the individual freedom that it claims to defend. I begin by reconstructing the Hegelian concept of freedom from its most general lines, showing (...) that being free consists in wanting to become someone and not so much in wanting to do something. After showing that the purpose of becoming someone can only be fulfilled in a social medium, I focus on Hegel's critique of the liberal state (as expounded in the section on “civil society”). I argue that civil society structurally impedes individuals from realizing their purpose of becoming someone: the economical interactions of civil society give rise to impersonal and inscrutable mechanisms, which take the social conditions of people's individuation beyond their control. Finally, I claim that (rational) individual freedom consists in being able to thematize and democratically control the very social conditions of individuation through the State and law. (shrink)

The question whether ethical behavior is biologically determined may refer either to the capacity for ethics (i.e., the proclivity to judge human actions as either right or wrong), or to the moral norms accepted by human beings for guiding their actions. I herein propose: (1) that the capacity for ethics is a necessary attribute of human nature; and (2) that moral norms are products of cultural evolution, not of biological evolution. Humans exhibit ethical behavior by nature because their biological makeup (...) determines the presence of three necessary conditions for ethical behavior: (i) the ability to anticipate the consequences of one’s own actions; (ii) the ability to make value judgments; and (iii) the ability to choose between alternative courses of action. Ethical behavior came about in evolution not because it is adaptive in itself, but as a necessary consequence of man’s eminent intellectual abilities, which are an attribute directly promoted by natural selection. That is, morally evolved as an exaptation, not as an adaptation. Since Darwin’s time there have been evolutionists proposing that the norms of morality are derived from biological evolution. Sociobiologists represent the most recent and most subtle version of that proposal. The sociobiologists' argument is that human ethical norms are sociocultural correlates of behaviors fostered by biological evolution. I argue that such proposals are misguided and do not escape the naturalistic fallacy. The isomorphism between the behaviors promoted by natural selection and those sanctioned by moral norms exist only with respect to the consequences of the behaviors; the underlying causations are completely disparate. (shrink)

Contemporary moral philosophy is split between an inherently a-historical moral philosophy/theory on the one hand and a growing interest in moral history and the historicity of morality on the other. In between these, the very moments of moral change are often left insufficiently attended to and under-theorized. Yet moral change is, arguably, one of the defining features of present day moral frameworks, and thus one of the main things we need to make sense of in moral philosophy. In this paper, (...) I present an account of moral change through the use of three metaphors: the tipping point, the bargaining table and the strong rope. I suggest these as coordinates for the development of a full-blown, historically sensitive conception of morality. (shrink)

How can it be that some acts of very high moral value are not morally required? This is the problem of supererogation. I do not argue in favor of a particular answer. Instead, I analyze two opposing moral intuitions the problem involves. First, that one should always do one’s best. Second, that sometimes we are morally allowed not to do our best. To think that one always has to do one’s best is less plausible, as it makes every morally best (...) act obligatory. I argue that, despite its implausibility, this is the main ingredient in a traditional outlook I call ‘morality of law,’ which conceives of morality as impartial, impersonal, rule-based and obligation-based. My main point is that supererogation will always be seen as problematic if the background theory is a morality of law. This is because supererogation encapsulates a view of morality-outside-obligation, whereas morality of law centers upon obligation as its main instrument of curbing a supposedly natural human selfishness. (shrink)

The aim of this paper is to present a perspective on Iris Murdoch conception of metaphysics, starting from her puzzling contention that she could describe herself as a ?Wittgensteinian Neo-Platonist?. I argue that this statement is a central clue to the nature both of her philosophical method which is strongly reminiscent of Wittgenstein's, and of her Platonism, which in its emphasis on the everyday and metaphorical aspects of his work differs starkly from received modern interpretations. Placing Murdoch between Plato and (...) Wittgenstein can help us to understand the nature of her metaphysics as a complex, continuous, pictorial activity, which shows a deep awareness of and is compatible with the late twentieth century and contemporary distrust of large metaphysical systems or explanations. (shrink)

Empirical research into moral decision-making is often taken to have normative implications. For instance, in his recent book, Greene (2013) relies on empirical findings to establish utilitarianism as a superior normative ethical theory. Kantian ethics, and deontological ethics more generally, is a rival view that Greene attacks. At the heart of Greene’s argument against deontology is the claim that deontological moral judgments are the product of certain emotions and not of reason. Deontological ethics is a mere rationalization of these emotions. (...) Accordingly Greene maintains that deontology should be abandoned. This paper is a defense of deontological ethical theory. It argues that Greene’s argument against deontology needs further support. Greene’s empirical evidence is open to alternative interpretations. In particular, it is not clear that Greene’s characterization of alarm-like emotions that are relative to culture and personal experience is empirically tenable. Moreover, it is implausible that such emotions produce specifically deontological judgments. A rival sentimentalist view, according to which all moral judgments are determined by emotion, is at least as plausible given the empirical evidence and independently supported by philosophical theory. I therefore call for an improvement of Greene’s argument. (shrink)

This paper argues that scientific realism commits us to a metaphysical determination relation between the mathematical entities that are indispensible to scientific explanation and the modal structure of the empirical phenomena those entities explain. The argument presupposes that scientific realism commits us to the indispensability argument. The viewpresented here is that the indispensability of mathematics commits us not only to the existence of mathematical structures and entities but to a metaphysical determination relation between those entities and the modal structure of (...) the physical world. The no-miracles argument is the primary motivation for scientific realism. It is a presupposition of this argument that unobservable entities are explanatory only when they determine the empirical phenomena they explain. I argue that mathematical entities should also be seen as explanatory only when they determine the empirical facts they explain, namely, the modal structure of the physical world. Thus, scientific realism commits us to a metaphysical determination relation between mathematics and physical modality that has not been previously recognized. The requirement to account for the metaphysical dependence of modal physical structure on mathematics limits the class of acceptable solutions to the applicability problem that are available to the scientific realist. (shrink)

Beginning with Barry Hoffmaster’s charge that we reclaim bioethics from the moral philosopher’s top-down theorizing, I discuss two moral philosophy contexts that offer resources for the kind of complex attention Hoffmaster demands: Iris Murdoch and Cora Diamond in moral philosophy and Margaret Urban Walker, Hilde Lindeman, and Marian Verkerk’s joint take on bioethics. My aim is: 1) to dispel a simplified notion of philosophy in bioethics; 2) to unite two strands of philosophy, which converge on important issues relevant to contemporary (...) bioethics; and 3) to explore these strands in terms of enabling, maieutic work on our ethical points of departure. (shrink)

Is there a choice in sexual orientation? [Wilkerson, William S. : “Is It a Choice? Sexual Orientation as Interpretation”. In: Journal of Social Philosophy 40. No. 1, p. 97–116] argues that sexual desires require interpretation in order to be fully constituted, and therefore sexual orientation is at least partially constituted by choice. [Díaz-León, Esa : “Sexual Orientation as Interpretation? Sexual Desires, Concepts, and Choice”; In: Journal of Social Ontology] critically assesses Wilkerson’s argument, concluding that we still lack a good argument (...) for the claim that choice plays a role in sexual orientation. Here I examine Díaz-León’s response to Wilkerson. I introduce what I call the conceptual act theory of sexual orientation, and argue that even if interpretation were not necessary to constitute sexual desires, it is a necessary element to constitute what we call sexual orientation. However, I conclude that even if we agree that interpretation is involved in sexual orientation, it does not follow that there is a choice involved. (shrink)

Multi-stakeholder initiatives have been praised as vehicles for tackling complex sustainability issues, but their success relies on the reconciliation of stakeholders’ divergent perspectives. We yet lack a thorough understanding of the micro-level mechanisms by which stakeholders can deal with these differences. To develop such understanding, we examine what frames—i.e., mental schemata for making sense of the world—members of MSIs use during their discussions on sustainability questions and how these frames are deliberated through social interactions. Whilst prior framing research has focussed (...) on between-frame conflicts, we offer a different perspective by examining how and under what conditions actors use shared frames to tackle ‘within-frame conflicts’ on views that stand in the way of joint decisions. Observations of a deliberative environmental valuation workshop and interviews in an MSI on the protection of peatlands—ecosystems that contribute to carbon retention on a global scale—demonstrated how the application and deliberation of shared frames during micro-level interactions resulted in increased salience, elaboration, and adjustment of shared frames. We interpret our findings to identify characteristics of deliberation mechanisms in the case of within-frame conflicts where shared frames dominate the discussions, and to delineate conditions for such dominance. Our findings contribute to an understanding of collaborations in MSIs and other organisational settings by demonstrating the utility of shared frames for dealing with conflicting views and suggesting how shared frames can be activated, fostered and strengthened. (shrink)

I will, first, outline what we currently know about the last 4 million years of human evolutionary history, from bipedal but small‐brained Australopithecus to modern Homo sapiens, our species, through the prolific toolmaker Homo habilis and the continent wanderer Homo erectus. I shall then identify anatomical traits that distinguish us from other animals and point out our two kinds of heredity, the biological and the cultural.Biological inheritance is based on the transmission of genetic information, in humans very much the same (...) as in other sexually reproducing organisms. But cultural inheritance is distinctively human, based on transmission of information by a teaching and learning process that is in principle independent of biological parentage. Cultural inheritance makes possible the cumulative transmission of experience from generation to generation. Cultural heredity is a swifter and more effective (because it can be designed) mode of adaptation to the environment than the biological mode. The advent of cultural heredity ushered in cultural evolution, which transcends biological evolution.I will, finally, explore ethical behavior as a model case of a distinctive human trait, and seek to ascertain the causal connections between human ethics and human biology. My conclusions are that (1) moral reasoning—that is, the proclivity to make ethical judgments by evaluating actions as either good or evil—is rooted in our biological nature; it is a necessary outcome of our exalted intelligence, but (2) the moral codes that guide our decisions as to which actions are good and which ones are evil are products of culture, including social and religious traditions. This second conclusion contradicts those evolutionists and sociobiologists who claim that the morally good is simply that which is promoted by the process of biological evolution. (shrink)

This paper sets forth a familiar theme, that science essentially consists of two interdependent episodes, one imaginative, the other critical. Hypotheses and other imaginative conjectures are the initial stage of scientific inquiry because they provide the incentive to seek the truth and a clue as to where to find it. But scientific conjectures must be subject to critical examination and empirical testing. There is a dialogue between the two episodes; observations made to test a hypothesis are the inspiration for new (...) conjectures. Inductive generalizations may also inspire hypotheses, but cannot validate them. A hypothesis is empirically tested by ascertaining whether or not predictions about the world of experience deduced from the hypothesis agree with what is actually observed. This has been appropriately considered the 'criterion of demarcation' that distinguishes science from other knowledge. But scientific hypotheses must satisfy other tests as well, e.g., whether they have explanatory value and further understanding. I briefly explore such issues as verifiability and falsifiability, empirical content and truthfulness, contingency and certainty, fact and theory, error and fraud. Science like any human activity is subject to error and to the foibles and other failings of human beings. But severe attempts of empirical falsification and other trials yield knowledge that stands the test of time and provides a foothold for further knowledge. Moreover, scientists have developed social mechanisms, such as peer review and publication, to evaluate their work. Because the research of scientists depends on the validity of previous knowledge, it is of great consequence that they discern valid from invalid knowledge and thus scientists are inclined to transcend ideology, nationality, friendship, monetary interest and other prejudices when the mettle of scientific knowledge is at stake. I use historical examples to illustrate some relevant aspects of scientific practice: its success (Mendel), misrepresentation (Darwin), ideological abuse (Lysenko), arrogant violation of the requirement of testing (Koch), theory replacement (Priestly and Lavoisier, Newton and Einstein), and the indispensability of context (Oswald Avery and Alfred Wegener). (shrink)

Dans l’édition historique et critique de Leibniz, la série I ( Correspondance générale, politique et historique ) est la série la plus volumineuse, la plus avancée et aussi la moins connue. Le fait qu’à côté des noms célèbres et des grandes problématiques qui concernent les autres séries de correspondances (philosophie ainsi que mathématiques et physique), elle contienne une foule de petites nouvelles et de correspondants de « second rang » a conduit dans le cours de l’édition à une critique fondamentale. (...) Cependant, non seulement parce que la multitude des thèmes reflète l’état du discours de l’époque, en deçà même du mainstream, et qu’entrent en scène nombre de « lettrés » dont l’activité serait autrement oubliée. Mais la conservation exceptionnellement bonne du fonds épistolaire rend aussi possible de suivre en détail le parcours des nouvelles. L’édition de Leibniz devient ainsi une ressource pour la République des Lettres et un atelier pour les recherches sur la culture épistolaire de l’époque. (shrink)

Knives, birds' wings, and mountain slopes are used for certain purposes: cutting, flying, and climbing. A bird's wings have in common with knives that they have been 'designed' for the purpose they serve, which purpose accounts for their existence, whereas mountain slopes have come about by geological processes independently of their uses for climbing. A bird's wings differ from a knife in that they have not been designed or produced by any conscious agent; rather, the wings, like the slopes, are (...) outcomes of natural processes without any intentional causation. Evolutionary biologists use teleological language and teleological explanations. I propose that this use is appropriate, because teleological explanations are hypotheses that can be subject to empirical testing. The distinctiveness of teleological hypotheses is that they account for the existence of a feature in terms of the function it serves; for example, wings have evolved and persist because flying is beneficial to birds by increasing their chances of surviving and reproducing. Features of organisms that are explained with teleological hypotheses include structures, such as wings; processes, such as development from egg to adult; and behaviours, such as nest building. A proximate explanation of these features is the function they serve; an ultimate explanation that they all share is their contribution to the reproductive fitness of the organisms. I distinguish several kinds of teleological explanations, such as natural and artificial, as well as bounded and unbounded, some of which but not others apply to biological explanations. (shrink)

Sex‐specific transcriptional and epigenomic profiles are detectable in the embryo very soon after fertilization. I propose that in male (XY) and female (XX) pre‐implantation embryos sex chromosomes establish sexually dimorphic interactions with the autosomes, before overt differences become apparent and long before gonadogenesis. Lineage determination restricts expression biases between the sexes, but the epigenetic differences are less constrained and can be perpetuated, accounting for dimorphisms that arise later in life. In this way, sexual identity is registered in the epigenome very (...) early in development. As development progresses, sex‐specific regulatory modules are harbored within shared transcriptional networks that delineate common traits. In reviewing this field, I propose that analyzing the mechanisms for sexual dimorphisms at the molecular and biochemical level and incorporating developmental and environmental factors will lead to a greater understanding of sex differences in health and disease. (shrink)

Causal structuralism is the view that, for each natural, non-mathematical, non-Cambridge property, there is a causal profile that exhausts its individual essence. On this view, having a property’s causal profile is both necessary and sufficient for being that property. It is generally contrasted with the Humean or quidditistic view of properties, which states that having a property’s causal profile is neither necessary nor sufficient for being that property, and with the double-aspect view, which states that causal profile is necessary but (...) not sufficient. Shoemaker’s (1998) and Hawthorne’s (2001) arguments in favor of causal structuralism primarily focus on problematic consequences of the other two views. I argue, however, that causation does not provide an appropriate framework within which to characterize all physical properties for two main reasons. First, there are physical properties that do not have causal profiles and properties whose causal profiles do not exhaust their essences. Second, there is no unified notion of causation across the sciences. After distinguishing between the causal and the nomological, I suggest that what is needed is a structuralist view of properties that is not merely causal but that incorporates a physical property’s higher-order mathematical and nomological properties into its identity conditions. Such a view retains the naturalistic motivations for causal structuralism while avoiding the problems it faces. (shrink)

Here the point of departure of Being and Time is criticized, i.e. the priority of Dasein in the determination of the meaning of being. An overview of Heidegger’s doctrine is offered, his concern for intentionality is acknowledged, then it takes place a critique of his starting point, and finally a Thomistic alternative account of intentionality is proposed.

Resumen: Este trabajo parte de reconocer la dificultad de trazar una fronte-ra nítida entre una caracterización conceptual académica especializada y el uso profano del término “populismo”. En la primera sección abordo el estatus problemático del tér-mino como concepto político y el significado peyorativo que siempre lo ha acompañado. En la segunda sección recorro de manera breve tres experien-cias históricas que se caracterizaron en su momento como “populistas”. En la última sección expongo mis dudas acerca de la posibilidad de revertir esa (...) carga peyorativa ligada al populismo y mi escepticismo ante los esfuerzos por utilizarlo como un contraconcepto para clasificar unidades políticas de acción, tal como se emplea para evaluar, en general de manera positiva, la innovación política en algunas experiencias latinoamericanas recientes.: It is not easy to draw a sharp line between the uses of the term “populism” in specialized academic research and in political struggles. In the first part of my contribution I underline the complex theoretical status of “populism” as a political concept and the pejorative sense that has always seemed to be attached to it. In the second part I briefly sketch three political experiences which were labelled as “populist” in their day. Finally, I express my doubts regarding the efforts to revert the pejorative sense of the concept and its use to describe and evaluate in generally positive terms the innovative character of some recent political experiences in Latin America. (shrink)

Consistency is usually seen as one of the hallmarks and a cardinal virtue of moral theory, as well as of any defensible real-life moral perspective. In everyday life a consistent set of moral beliefs is conductive to moral clarity, communicability, responsibility and responsiveness. But this is just one side of the story. In this paper I argue that inconsistency, properly understood, is a productive and constructive aspect of both moral philosophy and our moral lives. After an introductory glance at Ralf (...) Waldo Emerson and Hannah Arendt, the argument proceeds in three main steps. First, I discuss the philosophical importance of paying heed to inconsistencies in our moral lives, which often are prematurely pruned from moral philosophy. Second, I discuss the positive moral roles of inconsistency in terms of responsiveness to different situations, values, needs and concerns that call upon our attention in everyday life. Third, I argue that moral inconsistencies contribute to the necessary adaptability of our moral understandings to changing conditions. Fourth, in the place of a conclusion, I revisit the issue of consistency, clarity and accountability. (shrink)

The underrepresentation of women, people of color, and especially women of color—and the corresponding overrepresentation of white men—is more pronounced in philosophy than in many of the sciences. I suggest that part of the explanation for this lies in the role played by the idealized rational self, a concept that is relatively influential in philosophy but rarely employed in the sciences. The idealized rational self models the mind as consistent, unified, rationally transcendent, and introspectively transparent. I hypothesize that acceptance of (...) the idealized rational self leads philosophers to underestimate the influence of implicit bias on their own judgments and prevents them from enacting the reforms necessary to minimize the effects of implicit bias on institutional decision-making procedures. I consider recent experiments in social psychology that suggest that an increased sense of one’s own objectivity leads to greater reliance on bias in hiring scenarios, and I hypothesize how these results might be applied to philosophers’ evaluative judgments. I discuss ways that the idealized rational self is susceptible to broader critiques of ideal theory, and I consider some of the ways that the picture functions as a tool of active ignorance and color-evasive racism. (shrink)

Why I thought it useful to offer an explanation of Hegel’s doctrine on the Incarnation was so that the reader may be empowered to identify Hegel’s influence in modern accounts of this mystery. Even if, in my view, Hegel’s interpretation of revealed religion differs greatly from Catholic Doctrine, it is not surprising to find the presence of some of his concepts in modern theology. In truth, what matters is not the theologian’s self-identification as Hegelian or as non-Hegelian, but whether or (...) not the theologian adopts Hegel’s concepts. This paper offers an explanation of the internal dynamism of Hegelian concepts and their relation to Christian doctrine in Hegel’s Phenomenology of Spirit. This research may help to show in what way it is possible to explain Christian religious doctrine with a philosophy other than the Thomistic one and how, at least in Hegel’s case, religious doctrine is changed and reduced to an erroneous philosophical content. Also, an attempt is made to show the internal “coherence” of this Hegelian re-reading of Christianity so that theologians may become more cautious about accepting an explanation of Christian doctrine simply because the Christian language is preserved in that explanation. (shrink)

The question whether ethical behavior is biologically determined may refer either to the capacity for ethics (i.e., the proclivity to judge human actions as either right or wrong), or to the moral norms accepted by human beings for guiding their actions. I herein propose: (1) that the capacity for ethics is a necessary attribute of human nature; and (2) that moral norms are products of cultural evolution, not of biological evolution. Humans exhibit ethical behavior by nature because their biological makeup (...) determines the presence of three necessary conditions for ethical behavior: (i) the ability to anticipate the consequences of one’s own actions; (ii) the ability to make value judgments; and (iii) the ability to choose between alternative courses of action. Ethical behavior came about in evolution not because it is adaptive in itself, but as a necessary consequence of man’s eminent intellectual abilities, which are an attribute directly promoted by natural selection. That is, morally evolved as an exaptation, not as an adaptation. Since Darwin’s time there have been evolutionists proposing that the norms of morality are derived from biological evolution. Sociobiologists represent the most recent and most subtle version of that proposal. The sociobiologists' argument is that human ethical norms are sociocultural correlates of behaviors fostered by biological evolution. I argue that such proposals are misguided and do not escape the naturalistic fallacy. The isomorphism between the behaviors promoted by natural selection and those sanctioned by moral norms exist only with respect to the consequences of the behaviors; the underlying causations are completely disparate. (shrink)

En este trabajo me propongo desarrollar un estudio crítico de la concepción mecanicista de la explicación científica. En primer lugar, argumento que la caracterización mecanicista de los modelos fenoménicos (no explicativos) es inadecuada, pues no ofrece un análisis aceptable de los conceptos de modelo científico y similitud, que son fundamentales para la propuesta. En segundo lugar, sostengo que la caracterización de los modelos mecanicistas (explicativos) es igualmente inadecuada, pues los análisis disponibles de la relación explicativa de relevancia constitutiva implican una (...) tesis metafísica que es rechazada por los mismos mecanicistas. Concluyo que el mecanicismo no ofrece todavía una elucidación aceptable de la explicación científica. In this paper, I offer a critical assessment of the mechanicist approach to scientific explanation. Firstly, I argue that the mechanicist characterization of (non explanatory) phenomenological models is inadequate, since it does not develop an explication of the concepts of scientific model and similarity, which are indispensable to the approach. Secondly, I claim that the mechanicist conception of (explanatory) mechanicist models is inadequate as well, since all the available analices of the explanatory relation of constitutive relevance imply a metaphysical thesis that is rejected by the mechanicists themselves. I conclude that mechanicism needs to be emended if it aims to be considered as a genuinely illuminating approach to scientific explanation. (shrink)

Progress in neurotechnology and Artificial Intelligence (AI) provides unprecedented insights into the human brain. There are increasing possibilities to influence and measure brain activity. These developments raise multifaceted ethical and legal questions. The proponents of neurorights argue in favour of introducing new human rights to protect mental processes and brain data. This article discusses the necessity and advantages of introducing new human rights focusing on the proposed new human right to mental self-determination and the right to freedom of thought as (...) enshrined in Art.18 International Covenant on Civil and Political Rights (ICCPR) and Art. 9 European Convention on Human Rights (ECHR). I argue that the right to freedom of thought can be coherently interpreted as providing comprehensive protection of mental processes and brain data, thus offering a normative basis regarding the use of neurotechnologies. Besides, I claim that an evolving interpretation of the right to freedom of thought is more convincing than introducing a new human right to mental self-determination. (shrink)

In this paper I argue that the lack of interest, among analytic moral philosophers, in the contingencies of our moral present, produces an impoverished moral philosophy, unable to address the moral problems and quandaries of ordinary people. What is needed to remedy this is a broadening of the scope of the moral philosopher’s thought to include a rich attention to moral phenomena of the present. One such phenomenon, attended to by sociologists and critical journalists over the past few decades, is (...) the contemporary proliferating genre of psychologically oriented self-help literature. I display a range of sociological responses to self-help in order to point out aspects of morality that are made visible in these discussions, whereas they often remain invisible in standard moral philosophy. The aim is not to suggest a specific methodology for including such material into philosophical discussions, but rather to urge philosophers to reconsider the range of materials they attend to in their work, in order to produce a more lively engagement with and understanding of contemporary morality. (shrink)

Kant's claim that arithmetical truths are synthetic is famously contradicted by Frege, who considers them to be analytical. It may seem that this is a mere dispute about linguistic labels, since both Kant and Frege agree that arithmetical truths are a priori and informative, and, therefore, it is only a matter of how one chooses to call them. I argue that the choice between calling arithmetic “synthetic” or “analytic” has a deeper significance. I claim that the dispute is not a (...) merely linguistic one, but one involving the status of arithmetic as a science. Namely, it is a dispute about what truths are appropriate to use in grounding a scientific discipline. I interpret Frege's critique of Kant as being mainly about the lack of distinction between the context of justification and the context of discovery. (shrink)

St. Thomas Aquinas has always considered intelligence a potency higher than the will, absolutely speaking. That being said, and in my view, the existential primacy of the will in the act of freedom (particularly in choosing the existential end) is also indisputably Thomistic, as Cornelio Fabro has shown. This paper endeavors to explain Aquinas' doctrine on the absolute primacy of the intellect and thus show that these two primacies can be affirmed coherently, that is, the intellect’s absolute primacy and the (...) will’s existential primacy. Firstly, I will explain the reasoning St. Thomas Aquinas uses in the Summa to justify the absolute primacy of the intellect over the will. Secondly, I will explore some parallel texts, in order to shed light on my interpretation of the Summa and expand our view regarding this and related doctrinal points. Thirdly, I will offer a brief study of Fabro’s position, one in which his concerns regarding the intellect’s absolute primacy are taken into account and carefully considered. (shrink)